d_re71

Reaction state_transition d_re71 map

EXO1@default map EXO1|​S692_pho|​S372_pho|​S567_pho|​S587_pho@default map

Reaction regulators:

Catalysis
  1. CHEK2|​pho|​active@default map
  2. ATM|​pho|​S367_pho|​S1893_pho|​active@default map
  3. ATR|​pho|​active@Nucleus map
Modulation
  1. TP53BP1@default map



References
For inactivation of EXO1 by 53BP1-mediated phosphorylation:
PMID:18756267, PMID:15867354
ATM and ATR phosphorylate EXO1 and lead to EXO1 ubiquitination and degradation:
PMID:18048416, PMID:11438669, PMID:20019063

Confidence
REF=5 FUNC=4


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