d_re316

Reaction state_transition d_re316 map

CDC25C@default map CDC25C|​S216_pho@default map

Reaction regulators:

Catalysis
  1. CHEK1|​pho|​active@default map
  2. CHEK2|​pho|​active@default map



References
Phosphorylation of CDC25A, B or C by CHEK1 and CHEK2 inactivates CDC25, prevents activating de-phosphorylation of CDKs by CDC25 A, B, C
and stops cell cycle propagation
kegg cell cycle
PMID:20126263, PMID:17568790

Confidence
REF=1 FUNC=5


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