d_re163

Reaction state_transition d_re163 map

gFanconi_DNA_st4*@Nucleus map gFanconi_DNA_st5*@Nucleus map

Reaction regulators:

Catalysis
  1. REV1@default map
  2. POLZ*@default map
  3. FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​POLN@default map
  4. HEL308*:​POLQ@default map
Modulation
  1. BRCA1:​BRCA2:​FANCD2|​pho:​FANCI|​pho:​FANCJ*:​FANCN*:​RPA1:​RPA2:​RPA3@default map
Physical_stimulation
  1. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map



References
PMID:19686080
POLH activates D-loop extention
PoLN:HEL308* participate in HR and Fanconi. PolN:FANCD2:FANCI complex activate HR:
PMID:16337602
Presence of FA core complex is essential for thePolZ/Rev1 activity:
PMID:18448394
PoLQ/HEL308 in Fancon:
PMID:18472307

Confidence
REF=3 FUNC=3


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