d_re162

Reaction state_transition d_re162 map

gFanconi_DNA_st3*@Nucleus map gFanconi_DNA_st4*@Nucleus map

Reaction regulators:

Boolean_logic_gate_and
  1. EME1:​MSH2:​MSH3:​MUS81:​SNM1B*@default map and ERCC1:​MLH1:​PMS2:​XPF*@default map
Catalysis
  1. ERCC1:​MLH1:​PMS2:​XPF*@default map
  2. EME1:​MSH2:​MSH3:​MUS81:​SNM1B*@default map
  3. FANCJ*:​MLH1:​PMS2@default map
Modulation
  1. FANCA|​pho@default map
  2. FANCD2|​K561_ubi|​pho@default map
  3. MRE11*:​NBS1*|​S343_pho:​RAD50@default map
Physical_stimulation
  1. FANCJ*@default map



References
Link between HR, NER to Fanconi anemia pathway.
PMID:19686080
For ERCC1/XPF:
PMID:10882712, PMID:19805513
For MUS81/Eme1:
PMID:17036055:G
FANCA modulates XPF function:
MRN complex, FANCD2 and SNM1B are modulators of the DNA to release stalled fork:
PMD:19622404

Confidence
REF=3 FUNC=4


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