CYTOSKELETON_POLARITY

MAP:EMT_MOTILITY/MODULE:CYTOSKELETON_POLARITY map
During EMT, tightly zipped and largely immobile epithelial cells transform into highly mobile mesenchymal cells. The process requires excessive cytoskeletal rearrangement (PMID: 22949611, PMID: 20048336, PMID: 12663865), changing of cellular polarity from apical-basal into front-back to gain cell motility (PMID: 22172667).
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