Claudin2*

Protein Claudin2* map

Identifiers
claudin 2
HUGO:CLDN2 HGNC:2041 ENTREZ:9075 UNIPROT:P57739 GENECARDS:CLDN2 REACTOME:52234 ATLASONC:GC_CLDN2 WIKI:CLDN2

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CELL_CELL_ADHESIONS  map
 EMT  map  / TIGHT_JUNCTIONS  map

Claudin2*@Cytoplasm

References
e_re519( EMT  map ):
PMID:22671595
Caveolin-1 is an endocytic scaffolding protein
It binds independently to claudin-2 and occludin (co-immunoprecipitation assays).
The finding that caveolin-1 interacts with claudin-2 and occludin, but notwith claudin-4 or ZO-1, suggests a potential mechanism for selective retrieval of tight junction components.


Modifications:
In compartment: Cytoplasm
  1. Claudin2*@Cytoplasm map

In compartment: Extracellular space

  1. Claudin2*@Extracellular space map

  2. Claudin2*|​hm2@Extracellular space map

Participates in complexes:
In compartment: Cytoplasm

  1. Claudin2*:​Claudin3*@Cytoplasm map

  2. Claudin2*:​Occludin*@Cytoplasm map
  3. Caveolin1*:​Claudin2*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. Claudin2*@Extracellular space map + Claudin2*@Cytoplasm map map Claudin2*|​hm2@Extracellular space map

  2. Claudin2*@Cytoplasm map + Claudin3*@Cytoplasm map map Claudin2*:​Claudin3*@Cytoplasm map
  3. Occludin*@Cytoplasm map + Claudin2*@Cytoplasm map map Claudin2*:​Occludin*@Cytoplasm map
  4. Caveolin1*@Cytoplasm map + Claudin2*@Cytoplasm map map Caveolin1*:​Claudin2*@Cytoplasm map
  5. rClaudin2*@Nucleus map map Claudin2*@Cytoplasm map
  6. Occludin_Claudin1_2_4_5_7_8_16*@Cytoplasm map map Claudin2*@Cytoplasm map
  7. Claudin1_2_3_4*@Cytoplasm map map Claudin2*@Cytoplasm map
  8. Claudin2*:​Occludin*@Cytoplasm map map Tight junctions@Extracellular space map
  9. Claudin2*|​hm2@Extracellular space map map Tight junctions@Extracellular space map
  10. Claudin2*:​Claudin3*@Cytoplasm map map Tight junctions@Extracellular space map

As Catalyser:

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