Claudin1*

RNA Claudin1* map

Identifiers
claudin 1
HUGO:CLDN1 HGNC:2032 ENTREZ:9076 UNIPROT:O95832 GENECARDS:CLDN1 REACTOME:52232 KEGG:9076 ATLASONC:GC_CLDN1 WIKI:CLDN1

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CELL_CELL_ADHESIONS  map
 EMT  map  / TIGHT_JUNCTIONS  map

rClaudin1*@Nucleus

References
e_re523( EMT  map ):
PMID:12668723
Snail binds directly to the E-boxes of the promoters of claudin et occludin genes, resulting in complete repression of their promoter activity
PMID:16232121
Snail and Slug bind to the E-box motifs present in the human Claudin-1 promoter.
High levels of Snail and Slug correlatedwith lowlevels of Claudin-1 expression.
It is proposed that Claudin-1 is a direct downstream target gene of Snail family factors in epithelial cells
PMID:15151915
The transcription factors B-catenin/Tcf complex has been shown to bind directly to the claudin-1 and claudin-2 promoters.
PMID:17550342
SNAI2 represses Claudin-1 expression
SNAI1 represses Claudin-1 expression


Modifications:
In compartment: Nucleus
  1. rClaudin1*@Nucleus map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. gClaudin1*@Nucleus map map rClaudin1*@Nucleus map

    2. rClaudin1*@Nucleus map map Claudin1*@Cytoplasm map

    As Catalyser:

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