CK2_alpha_’*:CK2_alpha_*:CK_beta_*

Complex CK2_alpha_’*:CK2_alpha_*:CK_beta_* map


Complex composition:

  1. CK_beta_* map
  2. CK2_alpha_* map
  3. CK2_alpha_’* map




CK2_alpha_’*:​CK2_alpha_*:​CK_beta_*@Nucleus

Identifiers
NAME:CK2_alpha_:CK2_alpha_*:CK_beta_*

References
casein kinase 2
a_re1483:( Apoptosis  map ) PMID:18411308

Confidence
REF=1 FUNC=4

CK2_alpha_’*:​CK2_alpha_*:​CK_beta_*@Cytoplasm

Identifiers
NAME:CK2_alpha_:CK2_alpha_*:CK_beta_*

References
casein kinase 2
a_re248( Apoptosis  map ):
PMID:15637053
in human fibrosarcoma HT1080 cells, phosphorylation of GPI by CK2 decreases its enzymatic activity and (non-phosphorylatable or phospho-mimetic mutants)
in HT1080, knock-down of CK2 promotes GPI activity
in vitro, in HT1080 cells, phosphomimetic GPI mutant forms tetramers
in vitro, CK2 triggers GPI tetramerisation
PMID:11004567
in vitro CK2 mediated phosphorylation of GPI on S185
in HT1080 cells, Ser phosphorylation of GPI
a_re509( Apoptosis  map ):
PMID:11583622
BID phosphorylated in Hela, in L929 (murine fibrosarcoma cell line), in other cell lines
mass spectrometry analysis of BID phosphorylated in vitro by Jurkat or Hela extracts
mutagenesis experiments identifies S61 and S64 as the main phosphorylation site
purification of kinase activity in 3 different chromatography fractions
CSNK inhibits Fas-induced apoptosis in Hela D98/AH2 (Fas sensitive Hela)
PMID:12598529
by CSNK2 at T59
PMID:20356928

Confidence
REF=5 FUNC=4


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. CK2_alpha_’*:​CK2_alpha_*:​CK_beta_*@Cytoplasm map

In compartment: Nucleus

  1. CK2_alpha_’*:​CK2_alpha_*:​CK_beta_*@Nucleus map

Participates in reactions:
As Reactant or Product:

    As Catalyser:

    1. MDC1@Nucleus map map MDC1|​Nter-SDT-motifs_pho@Nucleus map

    2. GPI|​hm2@Cytoplasm map map GPI|​S185_pho|​hm4@Cytoplasm map
    3. BID@Cytoplasm map map BID|​pho@Cytoplasm map

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