CK1_epsilon_*:CTHRC1:DVL*:PRR*:ROR2:RSPO3:SYN4*:VANGL*:_beta_-Arrestin2*

Complex CK1_epsilon_*:CTHRC1:DVL*:PRR*:ROR2:RSPO3:SYN4*:VANGL*:_beta_-Arrestin2* map


Complex composition:

  1. DVL* map
  2. ROR2 map
  3. CK1_epsilon_* map
  4. CTHRC1 map
  5. SYN4* map
  6. VANGL* map
  7. _beta_-Arrestin2* map
  8. RSPO3 map
  9. PRR* map




CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​PRR*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​_beta_-Arrestin2*@Cytoplasm

Identifiers
NAME:CK1_epsilon_*:CTHRC1:DVL*:PRR*:ROR2:RSPO3:SYN4*:VANGL*:_beta_-Arrestin2*

References
PCP MODULE
s_wnc1_re111( Survival  map ):
Rspo is required for clathrin-mediated endocytosis
PMID:21397842
It has been shown that Dvl polymers are not associated with vesicles, therefore endocytosis of the complex is likely to be after Dvl polymerisation.
PMID:16263762
s_wnc1_re112( Survival  map ):
Clathrin-mediated endocytosis
PMID:20947020
PMID:19910923
PCP MODULE splits in Rac1 branch when Dvl is not hyper-phosphorylated
PMID:18953287
s_wnc1_re114( Survival  map ):
RhoA branch of the PCP -MODULE when Dvl is hyper-phosphorylated by CK_epsilon
s_s_wnc1_re112( Survival  map ):
s_s_wnc1_re114( Survival  map ):

Confidence
REF=5 FUNC=2


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​PRR*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​_beta_-Arrestin2*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​PRICKLE1|​pho|​ubi:​PRR*:​ROR2:​SYN4*:​VANGL*:​_beta_-Arrestin2*@Cytoplasm map + RSPO3@Cytoplasm map map CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​PRR*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​_beta_-Arrestin2*@Cytoplasm map + SMURF1@Cytoplasm map + PRICKLE1|​pho|​ubi@Cytoplasm map

  2. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​PRR*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​_beta_-Arrestin2*@Cytoplasm map map CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​FZD*:​PAR6*:​PRR*:​RACK1*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Endosome map
  3. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​PRR*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​_beta_-Arrestin2*@Cytoplasm map map CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​pho|​pho:​FZD*:​PAR6*:​PRR*:​RACK1*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Endosome map

As Catalyser:

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