CK1_epsilon_*:CTHRC1:DVL*:FZD*:PAR6*:PRR*:RAC1:RACK1*:ROR2:RSPO3:SYN4*:VANGL*:WNT*:_beta_-Arrestin2*

Complex CK1_epsilon_*:CTHRC1:DVL*:FZD*:PAR6*:PRR*:RAC1:RACK1*:ROR2:RSPO3:SYN4*:VANGL*:WNT*:_beta_-Arrestin2* map


Complex composition:

  1. FZD* map
  2. ROR2 map
  3. WNT* map
  4. CTHRC1 map
  5. SYN4* map
  6. VANGL* map
  7. RACK1* map
  8. PAR6* map
  9. CK1_epsilon_* map
  10. _beta_-Arrestin2* map
  11. DVL* map
  12. PRR* map
  13. RSPO3 map
  14. RAC1 map




CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​FZD*:​PAR6*:​PRR*:​RAC1:​RACK1*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Endosome

Identifiers
NAME:CK1_epsilon_*:CTHRC1:DVL*:FZD*:PAR6*:PRR*:RAC1:RACK1*:ROR2:RSPO3:SYN4*:VANGL*:WNT*:_beta_-Arrestin2*

References
PCP MODULE
s_wnc1_re108( Survival  map ):
Rac1 found to be associated with polymerised Dvl.
PMID:20215527
PMID:18953287
DEP domain in Dvl is enough to activate Rac
PMID:12533515
s_wnc1_re119( Survival  map ):
PRR binds to subunits ATP6V0C/D of the ATPase to lower the pH in the endosome. The reason for this is unknown but it is speculated that a lower pH is required for remodeling of the actin skeleton. However, v-ATPase is necessary for signaling
PMID:21796133
PMID:21380625
PMID:20093472

Confidence
REF=4 FUNC=2


Modifications:
Participates in complexes:
In compartment: Endosome
  1. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​FZD*:​PAR6*:​PRR*:​RAC1:​RACK1*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Endosome map

Participates in reactions:
As Reactant or Product:

  1. RAC1@Cytoplasm map + CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​FZD*:​PAR6*:​PRR*:​RACK1*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Endosome map map CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​FZD*:​PAR6*:​PRR*:​RAC1:​RACK1*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Endosome map

  2. CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​FZD*:​PAR6*:​PRR*:​RAC1:​RACK1*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Endosome map map RAC1@Cytoplasm map + CK1_epsilon_*:​CTHRC1:​DVL*|​pho|​emp|​emp:​FZD*:​PAR6*:​PRR*:​RACK1*:​ROR2:​RSPO3:​SYN4*:​VANGL*:​WNT*:​_beta_-Arrestin2*@Endosome map

As Catalyser:

  1. ATP6V0C_D*@Cytoplasm map map ATP6V0C_D*@Endosome map

  2. ATP6V0C_D*@Cytoplasm map map ATP6V0C_D*@Endosome map

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