CELL_CELL_ADHESIONS

MAP:EMT_MOTILITY/MODULE:CELL_CELL_ADHESIONS map
During EMT, tightly zipped and largely immobile epithelial cells transform into highly mobile mesenchymal cells. The process requires disruption of cell-cell adhesions (PMID: 18050482), including tight junctions (PMID: 17950242, PMID: 17945185, PMID: 15151915), adherens junctions (PMID: 22770731, PMID: 20066120, PMID: 16325582), desmosomes (PMID: 19955337) and gap junctions (PMID: 20066080, PMID: 14576341, PMID: 22935924).
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