CDK6:CyclinD*:p27KIP1*

Complex CDK6:CyclinD*:p27KIP1* map


Complex composition:

  1. CyclinD* map
  2. CDK6 map
  3. p27KIP1* map




CDK6:​CyclinD*:​p27KIP1*@Nucleus

Identifiers
NAME:CDK6:CyclinD*:p27KIP1*

Maps_Modules
 Cell cycle  map  / P27KIP  map

References
c_re181( Cell cycle  map ):
The complex CYCLIND-CDK stability increases when bound to a Cip/Kip family member.
PMID:10385618
c_re174( Cell cycle  map ):
CDK activity stimulated by its CAK-complex phosphorylation.
PMID:12459251, PMID:16782892

Confidence
REF=1 FUNC=4

CDK6|​Thr_pho:​CyclinD*:​p27KIP1*@Nucleus

Identifiers
NAME:CDK6:CyclinD*:p27KIP1*

Maps_Modules
 Cell cycle  map  / P27KIP  map
 Cell cycle  map  / RB  map

References
c_re174( Cell cycle  map ):
CDK activity stimulated by its CAK-complex phosphorylation.
PMID:12459251, PMID:16782892
c_re92:( Cell cycle  map ) PMID:12006580
c_re298( Cell cycle  map ):
Phosphorylation of pRB
PMID:9315635
dissociation of HDAC1 (during the G1 to S transition)
PMID:10778858, PMID:11520855, PMID:7736585, PMID:9425340, PMID:9190208

Confidence
REF=5 FUNC=4


Modifications:
Participates in complexes:
In compartment: Nucleus
  1. CDK6:​CyclinD*:​p27KIP1*@Nucleus map

  2. CDK6|​Thr_pho:​CyclinD*:​p27KIP1*@Nucleus map

Participates in reactions:
As Reactant or Product:

  1. CDK6:​CyclinD*:​p27KIP1*@Nucleus map map CDK6|​Thr_pho:​CyclinD*:​p27KIP1*@Nucleus map

  2. p27KIP1*@Nucleus map + CDK6:​CyclinD*@Nucleus map map CDK6:​CyclinD*:​p27KIP1*@Nucleus map

As Catalyser:

  1. DP2*:​E2F4:​SIN3B:​SUV39H1:​p130*@Nucleus map map DP2*:​E2F4:​SIN3B:​SUV39H1:​p130*|​pho@Nucleus map

  2. BAF250*:​DP1*:​E2F1:​RB1|​pho@Nucleus map map HDAC1@Nucleus map + BAF250*:​DP1*:​E2F1:​RB1|​pho|​pho@Nucleus map
  3. DP2*:​E2F4:​p107*@Nucleus map map DP2*:​E2F4:​p107*|​pho@Nucleus map

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