CDK5

Protein CDK5 map

Identifiers
cyclin-dependent kinase 5
HUGO:CDK5 HGNC:1774 ENTREZ:1020 UNIPROT:Q00535 GENECARDS:CDK5 REACTOME:69449 KEGG:1020 ATLASONC:GC_CDK5 WIKI:CDK5

Maps_Modules
 DNA repair  map  / BER  map

References
Triple phosphorylation by CDK5 inhibits PARP1
PMID:21922195
Stabilisation of USP1 by phosphorylaton by CDK5
PMID:23589330

CDK5@default

References
d_re36( DNA repair  map ):
PMID:16332722
Auto-phosphorylation of ATM in response to DNA DSB:
PMID:17303408, PMID:12556884, PMID:16858402
Amplification of ATM auto-phosphorylation by the complex ATM:MRNcomplex:H2AX:MDC1CDK5 phosphorylates and activates ATM
PMID:19151707
d_re554:( DNA repair  map ) PMID:21727086, PMID:21922195, PMID:20724832
d_re555( DNA repair  map ):
Triple phosphorylation by CDK5 inhibits PARP1
PMID:21922195
d_re565( DNA repair  map ):
Stabilisation by phosphorylaton by CDK5
PMID:23589330


Modifications:
In compartment: default
  1. CDK5@default map

Participates in complexes:
In compartment: default

  1. CDK5:​EME1:​STAT3|​Ser727_pho@default map

Participates in reactions:
As Reactant or Product:

  1. EME1@default map + STAT3|​Ser727_pho@default map + CDK5@default map map CDK5:​EME1:​STAT3|​Ser727_pho@default map

As Catalyser:

  1. gHR_DNA_st5*@Nucleus map map gHR_DNA_st6*@Nucleus map

  2. ATM@default map map ATM|​pho|​S367_pho|​S1893_pho|​active@default map
  3. APE*@default map map APE*|​Thr233_pho|​ubi@default map
  4. PARP1@Nucleus map map PARP1|​Ser782_pho|​Ser786_pho|​Ser785_pho@default map
  5. USP1@default map map USP1|​pho@default map

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