CDK4_6*:CIP1_KIP1*:CyclinD*

Complex CDK4_6*:CIP1_KIP1*:CyclinD* map


Complex composition:

  1. CDK4_6* map
  2. CyclinD* map
  3. CIP1_KIP1* map




(CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@default

Identifiers
NAME:CDK4_6*:CIP1_KIP1*:CyclinD*

Maps_Modules
 DNA repair  map  / G1_S_CHECKPOINT  map
 DNA repair  map  / G1_CC_PHASE  map

References
p53-dependentG1/S checkpoint
d_re115( DNA repair  map ):
PMID:16581787,
For inhibition of S-checkpoint by ATM:
PMID:15175241
Inhibition of Sphase by MRE complex:
PMID:17713585
By CycE*/CDK2: G1/S transition
By CycD*/CDK2/CIp/KIP: checkpoint G1/S

Confidence
REF=2 FUNC=5


Modifications:
Participates in complexes:
In compartment: default
  1. (CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@default map

Participates in reactions:
As Reactant or Product:

  1. (CDK4_6*|​T172_pho:​CyclinD*)|​active@default map + CIP1_KIP1*@default map map (CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@default map

  2. (CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@default map map CIP1_KIP1*@default map + (CDK4_6*|​T172_pho:​CyclinD*)|​active@default map

As Catalyser:

  1. G1 phase@default map map S phase@default map

  2. E2F1:​RB1@default map map E2F1:​RB1|​pho@default map
  3. E2F4_5*:​p107*@default map map E2F4_5*:​p107*|​pho@default map

Leave a Reply