CDC42_GAPs*

Protein CDC42_GAPs* map

Identifiers
CDC42_GAPs*
Rho GTPase activating protein 1
HUGO:ARHGAP1 HGNC:673 ENTREZ:392 UNIPROT:Q07960 GENECARDS:ARHGAP1 REACTOME:63060 KEGG:392 ATLASONC:GC_ARHGAP1 WIKI:ARHGAP1
Rho GTPase activating protein 5
GFI2, “growth factor independent 2″
HUGO:ARHGAP5 HGNC:675 ENTREZ:394 UNIPROT:Q13017 GENECARDS:ARHGAP5 REACTOME:195107 KEGG:394 ATLASONC:GC_ARHGAP5 WIKI:ARHGAP5
Rho GTPase activating protein 17
HUGO:ARHGAP17 HGNC:18239 ENTREZ:55114 UNIPROT:Q68EM7 GENECARDS:ARHGAP17 REACTOME:408043 KEGG:55114 ATLASONC:GC_ARHGAP17 WIKI:ARHGAP17
Rho GTPase activating protein 31
HUGO:ARHGAP31 HGNC:29216 ENTREZ:57514 UNIPROT:Q2M1Z3 GENECARDS:ARHGAP31 REACTOME:195149 KEGG:57514 WIKI:ARHGAP31
Rho GTPase activating protein 32
HUGO:ARHGAP32 HGNC:17399 ENTREZ:9743 UNIPROT:A7KAX9 GENECARDS:ARHGAP32 REACTOME:385957 KEGG:9743 ATLASONC:GC_ARHGAP32 WIKI:ARHGAP32
breakpoint cluster region
BCR1, D22S11
HUGO:BCR HGNC:1014 ENTREZ:613 UNIPROT:P11274 GENECARDS:BCR REACTOME:50776 KEGG:613 ATLASONC:BCR WIKI:BCR
ralA binding protein 1
HUGO:RALBP1 HGNC:9841 ENTREZ:10928 UNIPROT:Q15311 GENECARDS:RALBP1 REACTOME:99721 KEGG:10928 ATLASONC:GC_RALBP1 WIKI:RALBP1
active BCR-related
HUGO:ABR HGNC:81 ENTREZ:29 UNIPROT:Q12979 GENECARDS:ABR REACTOME:405546 KEGG:29 ATLASONC:GC_ABR WIKI:ABR
chimerin 2
HUGO:CHN2 HGNC:1944 ENTREZ:1124 UNIPROT:P52757 GENECARDS:CHN2 REACTOME:404336 KEGG:1124 ATLASONC:GC_CHN2 WIKI:CHN2
deleted in liver cancer 1
HUGO:DLC1 HGNC:2897 ENTREZ:10395 UNIPROT:Q96QB1 GENECARDS:DLC1 REACTOME:63068 KEGG:10395 ATLASONC:DLC1ID40328ch8p22 WIKI:DLC1

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CYTOSKELETON_POLARITY  map

CDC42_GAPs*@Cytoplasm

References
e_re874( EMT  map ):
PMID:8537347
PMID:10769036
ARHGAP5 as a GAP of CDC42
e_re875( EMT  map ):
PMID:12857875
ARHGAP32 as a GAP of CDC42
e_re878( EMT  map ):
PMID:7479768
PMID:8262969
ABR and BCR as a GAP of CDC42
e_re879( EMT  map ):
e_re880( EMT  map ):
PMID:16519628
ARHGAP31 as a GAP of CDC42
e_re881( EMT  map ):
PMID:16678097
ARHGAP17 as a GAP of CDC42
e_re882( EMT  map ):
PMID:14633674
DLC1as a GAP of CDC42
e_re883( EMT  map ):
PMID:10551883
FGFR1 regulates activity of CDC42 by binding and phosphorylating thus inactivating BCL2.
Phosphorylated BCL2 binds to another CDC42_GAP, ARHGAP1 and neutralize the GAP activity of ARHGAP1 as well.


Modifications:
In compartment: Cytoplasm
  1. CDC42_GAPs*@Cytoplasm map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. CDC42_GAPs*@Cytoplasm map map ARHGAP1@Cytoplasm map

    2. CDC42_GAPs*@Cytoplasm map map ARHGAP5@Cytoplasm map
    3. CDC42_GAPs*@Cytoplasm map map ARHGAP32|​Y_pho@Cytoplasm map
    4. CDC42_GAPs*@Cytoplasm map map RALBP1@Cytoplasm map
    5. CDC42_GAPs*@Cytoplasm map map CHN2@Cytoplasm map
    6. CDC42_GAPs*@Cytoplasm map map ABR@Cytoplasm map
    7. CDC42_GAPs*@Cytoplasm map map BCR@Cytoplasm map
    8. CDC42_GAPs*@Cytoplasm map map ARHGAP31@Cytoplasm map
    9. CDC42_GAPs*@Cytoplasm map map ARHGAP17@Cytoplasm map
    10. CDC42_GAPs*@Cytoplasm map map DLC1@Cytoplasm map
    11. CDC42_GAPs*@Cytoplasm map map BNIP2@Cytoplasm map

    As Catalyser:

    1. CDC42:​GTP@Cytoplasm map map CDC42:​GDP@Cytoplasm map

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