e_re521( EMT ):
The phosphorylation of caveolin-1 served to recruit C-terminal Src-like kinase (Csk) to the integrin/caveolin-1 complex.
This recruitment results in additional regulation of SFK activity and induction of myosin light chain (MLC) phosphorylation.
Key components of this pathway were recruited to caveolar microdomains and dependent on the presence of the caveolin-1 protein.
p190RhoGAP links integrins and caveolin-1 (and thus caveolae) to RhoA in a mechanotransduction cascade
Participates in complexes:
In compartment: Cytoplasm
Participates in reactions:
As Reactant or Product: