Caspase3*

Protein Caspase3* map

Identifiers
caspase 3, apoptosis-related cysteine peptidase
“caspase 3, apoptosis-related cysteine protease”
HUGO:CASP3 HGNC:1504 ENTREZ:836 UNIPROT:P42574 GENECARDS:CASP3 REACTOME:57022 KEGG:836 ATLASONC:GC_CASP3 WIKI:CASP3
HGNC:1504 ENTREZ:836 UNIPROT:P42574

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CYTOSKELETON_POLARITY  map
 Apoptosis  map  / CASPASES  map
 Survival  map  / MAPK  map
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:11989976
PMID:17959595
Caspase1,3 promote proteosomal degradation of ARHGDIB
CASPASE3 cleaves KSR1 in apoptotic cells. Thus MEK is sequestered in the cytosol and its interaction with Raf and ERK is prevented.
PMID:17613518
PMID:9765224

Caspase3*|​-SNO@Cytoplasm

References
a_re1024:( Apoptosis  map ) PMID:10213689


Modifications:
In compartment: Cytoplasm
  1. Caspase3*@Cytoplasm map

  2. Caspase3*|​-SNO@Cytoplasm map

Participates in complexes:
In compartment: Cytoplasm

  1. Caspase3*:​HSPB1@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. Caspase3*@Cytoplasm map + NO@Cytoplasm map map Caspase3*|​-SNO@Cytoplasm map

  2. Caspase3*@Cytoplasm map + HSPB1@Cytoplasm map map Caspase3*:​HSPB1@Cytoplasm map
  3. Caspase3*@Cytoplasm map map Caspase3_cl_uncl*@Cytoplasm map
  4. rCaspase3*@Nucleus map map Caspase3*@Cytoplasm map
  5. Caspase3*@Cytoplasm map map cleaved~Caspase3*@Cytoplasm map
  6. Caspase*@Cytoplasm map map Caspase3*@Cytoplasm map
  7. Caspase3*@Cytoplasm map map Caspase3*@Cytoplasm map
  8. p21CIP1*|​pho|​T146_pho@Cytoplasm map + Caspase3*@Cytoplasm map map s_s_akt1_s755
  9. Caspase3*@Cytoplasm map map Apoptosis@Mitochondria map
  10. Caspase3*@Cytoplasm map map Caspase3_sub_TRUNC_endsub_*@Cytoplasm map

As Catalyser:

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