Calmodulin*:KPNB1:NFAT*:PPP3R*:TNPO1:Tubulin-_alpha_*

Complex Calmodulin*:KPNB1:NFAT*:PPP3R*:TNPO1:Tubulin-_alpha_* map


Complex composition:

  1. NFAT* map
  2. PPP3R* map
  3. Calmodulin* map
  4. Tubulin-_alpha_* map
  5. KPNB1 map
  6. TNPO1 map




Calmodulin*:​KPNB1:​NFAT*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm

Identifiers
NAME:Calmodulin*:KPNB1:NFAT*:PPP3R*:TNPO1:Tubulin-_alpha_*

References
s_wnc2_re44( Survival  map ):
Tubulin-alpha binds both NFAT and KPNB1 after dephosphorylation of NFAT.
PMID:21278340
TNPO1 is a transport protein that helps in the import of proteins into the nucleus. Although it has been described with associated with NRON, it is most likely that it binds first to NFAT complex, making this complex ready for import, then NRON can bind to this complex to hinder the import of the complex
PMID:21709260
s_wnc2_re43:( Survival  map ) PMID:19136967
s_wnc2_re47( Survival  map ):
LRKK2 mediates binding of NFAT to NRON and other components, but this is independent of its kinase activity and independent of the phosphorylation status of NFAT
PMID:21983832

Confidence
REF=4 FUNC=2


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. Calmodulin*:​KPNB1:​NFAT*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. Calmodulin*:​KPNB1:​NFAT*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map map Ca2+:​Calmodulin*:​KPNB1:​NFAT*:​PPP3CB:​PPP3R*:​Tubulin-_alpha_*@Nucleus map

  2. Calmodulin*:​NFAT*:​PPP3R*@Cytoplasm map + KPNB1@Cytoplasm map + Tubulin-_alpha_*@Cytoplasm map + TNPO1@Cytoplasm map map Calmodulin*:​KPNB1:​NFAT*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map
  3. Calmodulin*:​KPNB1:​NFAT*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map + LRRK2@Cytoplasm map + rNRON@Cytoplasm map + CSE1L@Cytoplasm map map CSE1L:​Calmodulin*:​KPNB1:​LRRK2:​NFAT*:​NRON:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map

As Catalyser:

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