c_re218

Reaction state_transition c_re218 map

CDK1|​Thr14_pho:​CyclinB*@Nucleus map CDK1|​Tyr15_pho|​Thr14_pho:​CyclinB*@Nucleus map

Reaction regulators:

Catalysis
  1. WEE1@Nucleus map



Maps_Modules
 Cell cycle  map  / WEE  map
 Cell cycle  map  / CYCLINB  map

References
CDC2 phosphorylation at Tyr15 by WEE1, only when CDC2 is bound to a cyclin.
PMID:12814430
WEE1 allows CDC2 to stay in an inactive state after its translocation during G2.
PMID:10373560, PMID:8348613, PMID:9001210, PMID:1384126, PMID:15037762

Confidence
REF=5 FUNC=4


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