BRCA1

Gene BRCA1 map

Identifiers
breast cancer 1, early onset
HUGO:BRCA1 HGNC:1100 ENTREZ:672 UNIPROT:P38398 GENECARDS:BRCA1 REACTOME:50950 KEGG:672 ATLASONC:BRCA1ID163ch17q21 WIKI:BRCA1

Maps_Modules
 DNA repair  map  / G1_S_CHECKPOINT  map
 DNA repair  map  / S_PHASE_CHECKPOINT  map
 DNA repair  map  / G2_M_CHECKPOINT  map
 DNA repair  map  / HR  map
 DNA repair  map  / FANCONI  map

References
For S-phase checkpoint
PMID:11877377, PMID:15459660, PMID:19793801, PMID:20029420, PMID:21337561, PMID:21060331

gBRCA1@default

References
d_re232( DNA repair  map ):
p53 inhibits BRCA1 expression, this is a negative loop as response to the up-regulation and stabilization of p53 by BRCA1:
PMID:10884389, PMID:12496474
BRIT1*/E2F1 complex activates BRCA1 and CHEK1 transcription during S-phase and G2/M checkpoints:
PMID:15220350, PMID:18660752

gBRCA1@Gene compartment

References
c_re913:( Cell cycle  map ) PMID:12909625


Modifications:
In compartment: Gene compartment
  1. gBRCA1@Gene compartment map

In compartment: default

  1. gBRCA1@default map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. E2F4@Nucleus map map gBRCA1@Gene compartment map

    2. E2F1_alone@Cytoplasm map map gBRCA1@Gene compartment map
    3. E2F6@Nucleus map map gBRCA1@Gene compartment map
    4. gBRCA1@default map map rBRCA1@default map

    As Catalyser:

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