BLM

Protein BLM map

Identifiers
Bloom syndrome, RecQ helicase-like
HUGO:BLM HGNC:1058 ENTREZ:641 UNIPROT:P54132 GENECARDS:BLM REACTOME:50864 KEGG:641 ATLASONC:BLM109 WIKI:BLM

Maps_Modules
 DNA repair  map  / HR  map
 DNA repair  map  / FANCONI  map
 DNA repair  map  / TLS  map

References
For HR pathway, PMID:22657828
PMID:19772495, PMID:16697054, PMID:19847258
For Fanconi anemia pathway
PMID:19686080, PMID:19622404, PMID:18931676
FA core complex regulates REV1 and activated TLS
PMID:22266823
BLM in telomere maintenance
PMID:23253856
Resolving stalled replication fork


Modifications:
In compartment: default
  1. BLM@default map

Participates in complexes:
In compartment: default

  1. BLM:​EXO1@default map

  2. BLM:​RMI1:​TOP3A@default map
  3. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map
  4. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map

Participates in reactions:
As Reactant or Product:

  1. EXO1@default map + BLM@default map map BLM:​EXO1@default map

  2. TOP3A@default map + BLM@default map + RMI1@default map map BLM:​RMI1:​TOP3A@default map
  3. FANCA|​pho:​FANCG|​S7_pho@default map + FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@default map + FAAP24*:​FANCM@default map + FAAP100*:​FANCB:​FANCL@default map + BLM@default map + HES1@default map + FAAP20*@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map
  4. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map + TOP3A@default map + RPA1:​RPA2:​RPA3@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map
  5. BLM@default map map Telomere maintenance@Nucleus map

As Catalyser:

  1. gHR:​DNA:​st1*@default map map gHR:​DNA:​st2*@default map

  2. gHR:​DNA:​st5*@default map map gHR:​DNA:​st6*@default map
  3. gFanconi:​DNA:​st2*@default map map gFanconi:​DNA:​st3*@default map
  4. FANCD2|​pho@default map map FANCD2|​K561_ubi|​pho@default map
  5. FANCI|​pho@default map map FANCI|​K523_ubi|​pho@default map
  6. gFanconi:​DNA:​st4*@default map map gFanconi:​DNA:​st5*@default map
  7. FANCD2@default map map FANCD2|​pho@default map
  8. FANCD2|​K561_ubi|​pho@default map + MRE11*:​NBS1*|​S343_pho:​RAD50@default map + ATR|​pho|​active@default map map ATR|​pho:​FANCD2|​K561_ubi|​pho:​MRE11*:​NBS1*|​S343_pho:​RAD50@default map
  9. gTLS:​DNA:​st1*@default map map gTLS:​DNA:​st2*@default map

2 thoughts on “BLM

Comments are closed.