BIRC5:HBXIP

Complex BIRC5:HBXIP map


Complex composition:

  1. HBXIP map
  2. BIRC5 map




BIRC5|​T34_pho:​HBXIP@Cytoplasm

Identifiers
NAME:BIRC5:HBXIP

References
a_re668( Apoptosis  map ):
PMID:12773388
in vitro survivin_BIRC5 alone does not suppress CASP3/7/9 activities
in HepG2, interaction by coIP of endogenous proteins
in HEK293 or in vitro, preferential binding to T34 phosphorylated BIRC5, as determined through the use of unphosphorylatable or phosphomimetic mutants
in Hela expression of a dominant negative CDC2 decreases interaction
a_re484( Apoptosis  map ):
PMID:15210107
reviews the differerent hypothesis concerning the biochemical events leading to activation of CASP9
in vitro, survivin and HBXIP together inhibits CASP9 processing and activation
in HT1080 cells, coexpression of BIRC5 and HBXIP suppresses staurosporin-induced apoptosis
in cell extracts from Hela transfected with siRNA against HBXIP, CYCS induced caspase activation is suppressed
PMID:10329646
by NOD1

Confidence
REF=2 FUNC=0


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. BIRC5|​T34_pho:​HBXIP@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. HBXIP@Cytoplasm map + BIRC5|​T34_pho@Cytoplasm map map BIRC5|​T34_pho:​HBXIP@Cytoplasm map

As Catalyser:

  1. Caspase9*@Cytoplasm map map cleaved~Caspase9*@Cytoplasm map

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