BCL9

Protein BCL9 map

Identifiers
B-cell CLL/lymphoma 9
HUGO:BCL9 HGNC:1008 ENTREZ:607 UNIPROT:O00512 GENECARDS:BCL9 KEGG:607 ATLASONC:BCL9ID466 WIKI:BCL9

Maps_Modules
 Survival  map  / WNT_CANONICAL  map

BCL9@Nucleus

References
s_wca3_re4:( Survival  map ) PMID:15208637
s_wca3_re3( Survival  map ):
Upon wnt signalling beta-catenin is not degraded and can enter the nucleus
BCL9 and PYGO stimulate translocation of b-catenin.
PMID:15208637
No active transport of b-catenin localisation of b-catenin by retention of the binding partners
PMID:16554443

BCL9@Cytoplasm

References
s_wca3_re4:( Survival  map ) PMID:15208637


Modifications:
In compartment: Cytoplasm
  1. BCL9@Cytoplasm map

In compartment: Nucleus

  1. BCL9@Nucleus map

Participates in complexes:
In compartment: Nucleus

  1. BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map

  2. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  3. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  4. BCL9:​CBP*|​S92_pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map
  5. BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  6. BCL9:​PYGO*:​SMAD1|​pho:​TCF4:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  7. BCL9:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  8. BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map
  9. BCL9:​CTBP*:​KLF4:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​ace@Nucleus map
  10. BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  11. BCL9:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  12. BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_emp|​ace|​ace@Nucleus map
  13. APC|​T1487_pho:​BCL9:​CTBP*|​hm2:​DVL*:​HDAC1_2*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map

Participates in reactions:
As Reactant or Product:

  1. BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map + p300*@Nucleus map map BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map

  2. APC|​T1487_pho:​CTBP*|​hm2:​HDAC1_2*@Nucleus map + BCL9:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map map APC|​T1487_pho:​BCL9:​CTBP*|​hm2:​DVL*:​HDAC1_2*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  3. APC|​T1487_pho:​BCL9:​CTBP*|​hm2:​DVL*:​HDAC1_2*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map map APC|​T1487_pho:​_beta_-Catenin*|​K345_ace|​ace@Nucleus map + CTBP*:​p300*@Nucleus map + CTBP*:​HDAC1_2*:​LEF_TCF*:​WRE*@Nucleus map + DVL*:​JUN|​pho|​pho@Nucleus map
  4. BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map + CBP*|​S92_pho@Nucleus map map BCL9:​CBP*|​S92_pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map
  5. KLF8@Nucleus map + BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map + p300*@Nucleus map map BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  6. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map map BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  7. HDAC1_2*:​LEF_TCF*:​TLE*|​ubi:​WRE*@Nucleus map + BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map map BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_emp|​ace|​ace@Nucleus map + HDAC1_2*:​TLE*|​ubi@Nucleus map
  8. BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map + HDAC1_2*:​LEF_TCF*:​TLE*|​ubi:​WRE*@Nucleus map map BCL9:​KLF8|​K67_ace|​K93_ace|​K95_ace:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map + HDAC1_2*:​TLE*|​ubi@Nucleus map
  9. KLF4@Nucleus map + BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map + LEF_TCF*@Nucleus map + CTBP*@Nucleus map + gWRE*@Nucleus map map BCL9:​CTBP*:​KLF4:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​ace@Nucleus map
  10. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map + DVL*:​JUN|​pho|​pho@Nucleus map map BCL9:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map
  11. DVL*:​JUN|​pho|​pho@Nucleus map + BCL9:​CBP*|​S92_pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map map BCL9:​CBP*|​S92_pho:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​ace|​ace@Nucleus map
  12. BCL9@Cytoplasm map map BCL9@Nucleus map
  13. BCL9@Nucleus map + _beta_-Catenin*|​ace@Nucleus map + PYGO*@Nucleus map map BCL9:​PYGO*:​_beta_-Catenin*|​ace@Nucleus map
  14. HDAC1_2*:​LEF_TCF*:​TLE*|​ubi:​WRE*@Nucleus map + BCL9:​DVL*:​JUN|​pho|​pho:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map map BCL9:​DVL*:​JUN|​pho|​pho:​LEF_TCF*:​PYGO*:​WRE*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map + HDAC1_2*:​TLE*|​ubi@Nucleus map
  15. BCL9:​PYGO*:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map + SMAD1|​pho@Nucleus map map BCL9:​PYGO*:​SMAD1|​pho:​TCF4:​_beta_-Catenin*|​K345_ace|​ace:​p300*@Nucleus map

As Catalyser:

  1. gCyclinD*@Nucleus map map rCyclinD*@Nucleus map

  2. gAXIN1@Nucleus map map rAXIN1@Nucleus map
  3. gMMP9@Nucleus map map rMMP9@Nucleus map
  4. gGenes under control of _br_CBP-mediated transcription*@Nucleus map map rRNA@Nucleus map
  5. gTCF4@Nucleus map map rTCF4@Nucleus map
  6. gRAD6B*@Nucleus map map rRAD6B*@Nucleus map
  7. gBCL9@Nucleus map map rBCL9@Nucleus map
  8. gMIR372@Nucleus map map arMIR372@Nucleus map
  9. gMIR373@Nucleus map map arMIR373@Nucleus map
  10. gIRS2@Nucleus map map rIRS2@Nucleus map
  11. gCRIPTO-1*@Nucleus map map rCRIPTO-1*@Nucleus map
  12. _beta_-Catenin*@Cytoplasm map map _beta_-Catenin*@Nucleus map
  13. gMYC@Nucleus map map rMYC@Nucleus map
  14. gGene under control of_br_ P300-mediated transcription*@Nucleus map map rRNA@Nucleus map

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