BCL2L11

Protein BCL2L11 map

Identifiers
BCL2-like 11 (apoptosis facilitator)
HUGO:BCL2L11 HGNC:994 ENTREZ:10018 UNIPROT:O43521 GENECARDS:BCL2L11 REACTOME:401534 KEGG:10018 ATLASONC:BCL2L11ID772ch2q13 WIKI:BCL2L11

Maps_Modules
 Apoptosis  map  / APOPTOSIS_GENES  map
 Apoptosis  map  / CASPASES  map
 Apoptosis  map  / MITOCH_METABOLISM  map
 Apoptosis  map  / MOMP_REGULATION  map

References
synonym:BIM

BCL2L11|​S58_pho|​T56_pho|​S44_pho@Cytoplasm

References
a_re435:( Apoptosis  map ) reactionType:is.a

BCL2L11|​S58_unk|​T56_unk|​S44_unk@Cytoplasm

References
a_re435:( Apoptosis  map ) reactionType:is.a

BCL2L11|​ubi@Cytoplasm

References
a_re444:( Apoptosis  map ) PMID:18420585

BCL2L11@Mitochondrial outer membrane

References
a_re14( Apoptosis  map ):
PMID:15486085
in FL5.12 cells correlation of BIM-BAX interaction in mitochondrial fractions with presence of unphosphorylated S65 BimEL
non phosphorylatable BimEL: enhanced interaction with BAX and enhanced proapoptotic activity
PMID:12419244
in vitro in reconstituted vesicles, BID induces BAX and membrane permeabilization
a_re582( Apoptosis  map ):
PMID:9430630
BCL2-BimEL interaction in mitochondrial fraction independent of BIM S69 phosphorylation status
PMID:15724238
in human tonsil B cells, constitutive interaction
PMID:10198631
a_re583( Apoptosis  map ):
a_re586( Apoptosis  map ):
MCL1-BIM interaction in mitochondrial fraction independent of BIM S65 phosphorylation status


Modifications:
In compartment: Cytoplasm
  1. BCL2L11|​ubi@Cytoplasm map

  2. BCL2L11|​S58_pho|​T56_pho|​S44_pho@Cytoplasm map
  3. BCL2L11|​S58_unk|​T56_unk|​S44_unk@Cytoplasm map

In compartment: Mitochondrial outer membrane

  1. BCL2L11@Mitochondrial outer membrane map

Participates in complexes:
In compartment: Cytoplasm

  1. BCL2L11:​MIF@Cytoplasm map

  2. BCL2L11:​DYNLL1@Cytoplasm map
  3. BCL2L11|​S58_pho|​T56_pho|​S44_pho:​DYNLL1@Cytoplasm map

In compartment: Mitochondrial outer membrane

  1. BCL2:​BCL2L11@Mitochondrial outer membrane map

  2. BCL2L11:​MCL1@Mitochondrial outer membrane map
  3. BCL2A1:​BCL2L11@Mitochondrial outer membrane map
  4. BCL2L11:​BCL2L2@Mitochondrial outer membrane map
  5. BCL2-XL*:​BCL2L11@Mitochondrial outer membrane map

Participates in reactions:
As Reactant or Product:

  1. BCL2L11|​S58_pho|​T56_pho|​S44_pho@Cytoplasm map map BCL2L11|​ubi@Cytoplasm map

  2. rBCL2L11@Nucleus map map BCL2L11|​ubi@Cytoplasm map
  3. BCL2L11|​ubi@Cytoplasm map + MIF@Cytoplasm map map BCL2L11:​MIF@Cytoplasm map
  4. BCL2L11:​DYNLL1@Cytoplasm map map BCL2L11|​S58_pho|​T56_pho|​S44_pho:​DYNLL1@Cytoplasm map
  5. BCL2L11|​ubi@Cytoplasm map + DYNLL1@Cytoplasm map map BCL2L11:​DYNLL1@Cytoplasm map
  6. BCL2L11|​S58_pho|​T56_pho|​S44_pho:​DYNLL1@Cytoplasm map map DYNLL1@Cytoplasm map + BCL2L11|​S58_pho|​T56_pho|​S44_pho@Cytoplasm map
  7. BCL2L11|​S58_pho|​T56_pho|​S44_pho@Cytoplasm map map BCL2L11|​S58_unk|​T56_unk|​S44_unk@Cytoplasm map
  8. BimEL*@Cytoplasm map map BCL2L11|​ubi@Cytoplasm map
  9. BCL2L11|​ubi@Cytoplasm map map BCL2L11|​S58_unk|​T56_unk|​S44_unk@Cytoplasm map
  10. BCL2L11|​ubi@Cytoplasm map map degraded
  11. BimEL*|​ubi@Cytoplasm map map BCL2L11|​ubi@Cytoplasm map
  12. BCL2L11|​ubi@Cytoplasm map map BimEL*|​ubi@Cytoplasm map
  13. BCL2L11|​S58_unk|​T56_unk|​S44_unk@Cytoplasm map map BCL2L11|​ubi@Cytoplasm map
  14. BCL2L11@Mitochondrial outer membrane map + BCL2|​pho@Mitochondrial outer membrane map map BCL2:​BCL2L11@Mitochondrial outer membrane map
  15. BCL2L11@Mitochondrial outer membrane map + BCL2-XL*@Mitochondrial outer membrane map map BCL2-XL*:​BCL2L11@Mitochondrial outer membrane map
  16. BCL2L11@Mitochondrial outer membrane map + BCL2L2@Mitochondrial outer membrane map map BCL2L11:​BCL2L2@Mitochondrial outer membrane map
  17. BCL2L11@Mitochondrial outer membrane map + BCL2A1@Mitochondrial outer membrane map map BCL2A1:​BCL2L11@Mitochondrial outer membrane map
  18. BCL2L11@Mitochondrial outer membrane map + MCL1|​S159_unk@Mitochondrial outer membrane map map BCL2L11:​MCL1@Mitochondrial outer membrane map
  19. BCL2L11|​ubi@Cytoplasm map map BCL2L11@Mitochondrial outer membrane map

As Catalyser:

  1. BAX|​S163_unk|​T167_unk@Mitochondrial outer membrane map map a_s4588

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