BAIAP2

Protein BAIAP2 map

Identifiers
BAI1-associated protein 2
HUGO:BAIAP2 HGNC:947 ENTREZ:10458 UNIPROT:Q9UQB8 GENECARDS:BAIAP2 REACTOME:415617 KEGG:10458 ATLASONC:GC_BAIAP2 WIKI:BAIAP2

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CYTOSKELETON_POLARITY  map

BAIAP2@Cytoplasm

References
e_re788( EMT  map ):
Rac1 binds to BAIAP2 which in turn associates with WASF2.
This stimulates ARP2/3 and leads to actin cytoskeleal polymerization.
PMID:16702231
WAVE2 (so-called WASF2) activates the ARP2/3 complex for Rac-induced actin polymerization during lamellipodium formation
PMID:9843499
WASF (WAVE) as regulator of actin reorganization downstream of Rac.
Expressed WAVE induces the formation of actin filament clusters.
WAVE plays a critical role downstream of Rac in regulating the actin cytoskeleton required for mem- brane rufflin
PMID:12054568
WAVE2 serves a functional partner of IRSp53 by regulating its interaction with Rac.
e_re789( EMT  map ):
WAVE plays a critical role downstream of Rac in regulating the actin cytoskeleton required for mem- brane ruffling


Modifications:
In compartment: Cytoplasm
  1. BAIAP2@Cytoplasm map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. BAIAP2@Cytoplasm map map BAIAP2@Cytoplasm map

    As Catalyser:

    1. WASF2@Cytoplasm map map WASF2@Cytoplasm map

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