ATRIP

Protein ATRIP map

Identifiers
ATR interacting protein
HUGO:ATRIP HGNC:33499 ENTREZ:84126 UNIPROT:Q8WXE1 GENECARDS:ATRIP REACTOME:144344 ATLASONC:GC_ATRIP WIKI:ATRIP

Maps_Modules
 DNA repair  map  / S_PHASE_CHECKPOINT  map
 DNA repair  map  / G2_M_CHECKPOINT  map

References
For S-phase checkpoint
PMID:15459660, PMID:17384638, PMID:15798197, PMID:17102137, PMID:17116885, PMID:17296725, PMID:19793801, PMID:17582221, PMID:18677104

ATRIP@default

References
d_re260( DNA repair  map ):
DNA with O6-methylguanine adducts, MutSalpha and MutLalpha activate ATR/ATRIP and BER pathways performs the repair:
PMID:16713580, PMID:18543256
Damaged DNA triggers ATR/ATRIP complex activation


Modifications:
In compartment: default
  1. ATRIP@default map

Participates in complexes:
In compartment: default

  1. ATRIP:​ATR|​pho@default map

  2. ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​HCLK2*@default map
  3. ATRIP:​ATR|​pho:​CLSPN|​pho:​RAD17|​pho:​TOPBP1@default map
  4. ATRIP:​ATR|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3@default map
  5. ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​PCNA|​K164_ubi:​TIM1*@default map
  6. ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3:​TIM1*:​TIPIN@default map

Participates in reactions:
As Reactant or Product:

  1. ATR|​pho|​active@Nucleus map + ATRIP@default map map ATRIP:​ATR|​pho@default map

  2. TOPBP1@default map + ATRIP:​ATR|​pho@default map + CLSPN|​pho@default map + RAD17|​pho@default map map ATRIP:​ATR|​pho:​CLSPN|​pho:​RAD17|​pho:​TOPBP1@default map
  3. ATRIP:​ATR|​pho@default map + CLSPN|​pho@default map + RPA1:​RPA2:​RPA3@default map map ATRIP:​ATR|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3@default map
  4. HCLK2*@default map + CLSPN|​pho@default map + ATRIP:​ATR|​pho@default map + CHEK1|​pho|​active@default map map ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​HCLK2*@default map
  5. TIM1*@default map + CLSPN|​pho@default map + PCNA|​K164_ubi@default map + ATRIP:​ATR|​pho@default map + CHEK1|​pho|​active@Nucleus map map ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​PCNA|​K164_ubi:​TIM1*@default map
  6. ATRIP:​ATR|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3@default map + TIPIN@default map + TIM1*@default map + CHEK1|​pho|​active@default map map ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​RPA1:​RPA2:​RPA3:​TIM1*:​TIPIN@default map

As Catalyser:

  1. S phase@default map map G2 phase@default map

  2. G2 phase@default map map M phase@default map
  3. gDamaged_DNA*@Nucleus map map gRepaired_DNA*@Nucleus map
  4. CHEK1@default map map CHEK1|​pho|​active@default map
  5. ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*@default map + MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7@default map + CDT1@default map + CDC6@default map + CDC45@default map + POLA*@default map + PRIM*@default map + RPA1@Nucleus map + RPA2@Nucleus map + RPA3@Nucleus map map CDC45:​CDC6:​CDT1:​MCM2:​MCM3:​MCM4:​MCM5:​MCM6:​MCM7:​ORC1*:​ORC2*:​ORC3*:​ORC4*:​ORC5*:​ORC6*:​POLA*:​PRIM*:​RPA1:​RPA2:​RPA3@default map
  6. No DNA replicarion@default map map DNA replicarion@default map
  7. RAD1@default map + RAD9*|​pho@default map + HUS1@default map map HUS1:​RAD1:​RAD9*|​pho@default map
  8. HUS1:​RAD1:​RAD9*|​pho@default map + RAD17@default map + RFC*@Nucleus map map HUS1:​RAD1:​RAD17:​RAD9*:​RFC*@default map
  9. CLSPN@default map map CLSPN|​pho@default map
  10. gDeaminated_alkylated_mismatched_base*@Nucleus map map gBER_M-glyc_DNA_st2*@Nucleus map + Base@default map

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