ARP2_3*:Actin cytoskeletal*:Actinin*:BCAR1:FAK1*:PXN:Talin*:Vinculin*:c-SRC*

Complex ARP2_3*:Actin cytoskeletal*:Actinin*:BCAR1:FAK1*:PXN:Talin*:Vinculin*:c-SRC* map


Complex composition:

  1. ARP2_3* map
  2. Actinin* map
  3. Actin cytoskeletal* map
  4. c-SRC* map
  5. PXN map
  6. Vinculin* map
  7. Talin* map
  8. BCAR1 map
  9. FAK1* map




ARP2_3*:​Actin cytoskeletal*:​Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​Vinculin*:​c-SRC*@Cytoplasm

Identifiers
NAME:ARP2_3*:Actin cytoskeletal*:Actinin*:BCAR1:FAK1*:PXN:Talin*:Vinculin*:c-SRC*

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / ECM  map
 EMT  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:12473693
PMID:14749719
PMID:15094799
Vinculin recruits Arp2_3 complex to new sites of focal adhesions to nucleate new actin filaments, promoting actin polymerization.

Confidence
REF=3 FUNC=4


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. ARP2_3*:​Actin cytoskeletal*:​Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​Vinculin*:​c-SRC*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. ARP2_3*@Cytoplasm map + Actin cytoskeletal*:​Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​Vinculin*:​c-SRC*@Cytoplasm map map ARP2_3*:​Actin cytoskeletal*:​Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​Vinculin*:​c-SRC*@Cytoplasm map

  2. ARP2_3*:​Actin cytoskeletal*:​Actinin*:​BCAR1:​FAK1*|​Y_pho|​pho:​PXN|​pho:​Talin*:​Vinculin*:​c-SRC*@Cytoplasm map map Actin polymerization@Nucleus map

As Catalyser:

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