ARHGAP1

Protein ARHGAP1 map

Identifiers
Rho GTPase activating protein 1
HUGO:ARHGAP1 HGNC:673 ENTREZ:392 UNIPROT:Q07960 GENECARDS:ARHGAP1 REACTOME:63060 KEGG:392 ATLASONC:GC_ARHGAP1 WIKI:ARHGAP1

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CYTOSKELETON_POLARITY  map

References
PMID:9548756
RhoGAP1 (so-called ARHGAP1 or p50RhoGAP) is an RhoGTPase activiating protein.

ARHGAP1@Cytoplasm

References
e_re895( EMT  map ):
PMID:10551883
FGFR1 regulates activity of CDC42 by binding and phosphorylating thus inactivating BCL2.
Phosphorylated BCL2 binds to another CDC42_GAP, ARHGAP1 and neutralize the GAP activity of ARHGAP1 as well.


Modifications:
In compartment: Cytoplasm
  1. ARHGAP1@Cytoplasm map

Participates in complexes:
In compartment: Cytoplasm

  1. ARHGAP1:​BNIP2|​pho@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. RhoA_GAPs*@Cytoplasm map map ARHGAP1@Cytoplasm map

  2. Rac1_GAPs*@Cytoplasm map map ARHGAP1@Cytoplasm map
  3. CDC42_GAPs*@Cytoplasm map map ARHGAP1@Cytoplasm map
  4. ARHGAP1@Cytoplasm map + BNIP2|​pho@Cytoplasm map map ARHGAP1:​BNIP2|​pho@Cytoplasm map

As Catalyser:

    Leave a Reply