ADP

Simple molecule ADP map
ADP@Extracellular space

References
e_re122( EMT  map ):
PMID:12809600
PMID:22710166
The active ligand–receptor complex is a heterotetrameric complex
This complex consists of an active dimer of TGFB and homodimers of both TGFBRI and TGFBR2.
Within the active receptor complex, TGFBR2 autophosphorylates itself and catalyzes transphosphorylation of the TGFBR1.
Transphosphorylation of the TGFBRI activates its kinase activity.

ADP@Mitochondrial Matrix

Identifiers
CHEBI:16761 KEGGCOMPOUND:C00008 CAS:58-64-0

Maps_Modules
 Apoptosis  map  / APOPTOSIS_GENES  map
 Apoptosis  map  / MITOCH_METABOLISM  map
 Apoptosis  map  / TNF_RESPONSE  map

References
a_re981( Apoptosis  map ):
PMID:10838049
review

ADP@Mitochondrial intermembrane space

Identifiers
CHEBI:16761 KEGGCOMPOUND:C00008 CAS:58-64-0

Maps_Modules
 Apoptosis  map  / APOPTOSIS_GENES  map
 Apoptosis  map  / MITOCH_METABOLISM  map
 Apoptosis  map  / TNF_RESPONSE  map


Modifications:
In compartment: Cytoplasm
  1. ADP@Cytoplasm map

In compartment: Extracellular space

  1. ADP@Extracellular space map

In compartment: Mitochondrial Matrix

  1. ADP@Mitochondrial Matrix map

In compartment: Mitochondrial intermembrane space

  1. ADP@Mitochondrial intermembrane space map

In compartment: Nucleus

  1. ADP@Nucleus map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. L-cysteine@Cytoplasm map + L-glutamate@Cytoplasm map + ATP@Cytoplasm map map L-_gamma_-glutamyl-L-cysteine@Cytoplasm map + ADP@Cytoplasm map

    2. L-_gamma_-glutamyl-L-cysteine@Cytoplasm map + glycine@Cytoplasm map + ATP@Cytoplasm map map GSH@Cytoplasm map + ADP@Cytoplasm map
    3. ADP@Cytoplasm map map purine ribonucleoside 5′-diphosphate@Cytoplasm map
    4. purine 2′-deoxyribonucleoside 5′-diphosphate@Cytoplasm map + ATP@Cytoplasm map map purine 2′-deoxyribonucleoside 5′-triphosphate@Cytoplasm map + ADP@Cytoplasm map
    5. GDP@Cytoplasm map + ATP@Cytoplasm map map GTP@Cytoplasm map + ADP@Cytoplasm map
    6. ADP@Cytoplasm map map ATP@Cytoplasm map + AMP@Cytoplasm map
    7. ATP@Mitochondrial Matrix map + ADP@Mitochondrial intermembrane space map map ATP@Mitochondrial intermembrane space map + ADP@Mitochondrial Matrix map
    8. ATP@Mitochondrial intermembrane space map + ADP@Cytoplasm map map ATP@Cytoplasm map + ADP@Mitochondrial intermembrane space map
    9. glucose@Cytoplasm map + ATP@Cytoplasm map map glucose-6P@Cytoplasm map + ADP@Cytoplasm map
    10. fructose-6P@Cytoplasm map + ATP@Cytoplasm map map fructose-1,6P2@Cytoplasm map + ADP@Cytoplasm map
    11. fructose-6P@Cytoplasm map + ATP@Cytoplasm map map fructose-2,6P2@Cytoplasm map + ADP@Cytoplasm map
    12. glycerate-1,3P2@Cytoplasm map + ADP@Cytoplasm map map glycerate-3P@Cytoplasm map + ATP@Cytoplasm map
    13. phosphoenolpyruvate@Cytoplasm map + ADP@Cytoplasm map map pyruvate@Cytoplasm map + ATP@Cytoplasm map
    14. citrate@Cytoplasm map + ATP@Cytoplasm map + coenzyme A@Cytoplasm map map acetyl-CoA@Cytoplasm map + oxaloacetate@Cytoplasm map + ADP@Cytoplasm map
    15. acetyl-CoA@Cytoplasm map + NADPH@Cytoplasm map + ATP@Cytoplasm map + HCO3-@Cytoplasm map map long-chain fatty acid@Cytoplasm map + NADP_super_+_endsuper_@Cytoplasm map + CO_sub_2_endsub_@Cytoplasm map + coenzyme A@Cytoplasm map + ADP@Cytoplasm map
    16. ACLY@Cytoplasm map + ATP@Cytoplasm map map ACLY|​S454_pho@Cytoplasm map + ADP@Cytoplasm map
    17. ACO2|​oxidized@Mitochondrial Matrix map + ATP@Mitochondrial Matrix map map degraded + ADP@Mitochondrial Matrix map
    18. DLAT|​lipoylated:​DLD:​FAD:​PDHA*:​thiamine diphosphate@Mitochondrial Matrix map + ATP@Mitochondrial Matrix map map DLAT|​lipoylated:​DLD:​FAD:​PDHA*|​pho:​thiamine diphosphate@Mitochondrial Matrix map + ADP@Mitochondrial Matrix map
    19. L-glutamate@Cytoplasm map + ATP@Cytoplasm map + NH3@Cytoplasm map map L-glutamine@Cytoplasm map + ADP@Cytoplasm map
    20. PRDX3|​-SO2H@Mitochondrial Matrix map + ATP@Mitochondrial Matrix map map PRDX3|​-SOH@Mitochondrial Matrix map + ADP@Mitochondrial Matrix map
    21. PRDX*|​-SO2H@Cytoplasm map + ATP@Cytoplasm map map PRDX*|​-SOH@Cytoplasm map + ADP@Cytoplasm map
    22. COX4I1:​COX5A:​COX5B:​COX6A*:​COX6B*:​COX6C:​COX7A*:​COX7B*:​COX7C:​COX8*:​Cu2+:​MT-CO1:​MT-CO2:​MT-CO3:​heme a@Mitochondrial inner membrane map + COX4I2@Mitochondrial inner membrane map + ATP@Mitochondrial Matrix map map COX4I2:​COX5A:​COX5B:​COX6A*:​COX6B*:​COX6C:​COX7A*:​COX7B*:​COX7C:​COX8*:​Cu2+:​MT-CO1:​MT-CO2:​MT-CO3:​heme a@Mitochondrial inner membrane map + ADP@Mitochondrial Matrix map
    23. H+@Mitochondrial intermembrane space map + ADP@Mitochondrial Matrix map map H+@Mitochondrial Matrix map + ATP@Mitochondrial Matrix map
    24. H+@Mitochondrial Matrix map + ATP@Mitochondrial Matrix map map H+@Mitochondrial intermembrane space map + ADP@Mitochondrial Matrix map
    25. TGFB1|​hm2:​TGFBR1|​hm2:​TGFBR2|​hm2@Cytoplasm map + ATP@Extracellular space map map TGFB1|​hm2:​TGFBR1|​Ser_pho|​hm2:​TGFBR2|​Ser_pho|​hm2@Cytoplasm map + ADP@Extracellular space map
    26. SARA*:​SMAD2@Early Endosome map + ATP@Cytoplasm map map SARA*:​SMAD2|​S467_pho|​S465_pho@Early Endosome map + ADP@Cytoplasm map
    27. SARA*:​SMAD3@Early Endosome map + ATP@Cytoplasm map map SARA*:​SMAD3|​S423_pho|​S425_pho@Early Endosome map + ADP@Cytoplasm map
    28. Occludin*:​PARD6A:​TGFB1|​hm2:​TGFBR1|​hm2:​TGFBR2|​hm2@Cytoplasm map + ATP@Cytoplasm map map Occludin*:​PARD6A|​S345_pho:​TGFB1|​hm2:​TGFBR1|​Ser_pho|​hm2:​TGFBR2|​Ser_pho|​hm2@Cytoplasm map + ADP@Cytoplasm map
    29. RAF1|​closed@Cytoplasm map + ATP@Cytoplasm map map RAF1|​S_pho|​closed@Cytoplasm map + ADP@Cytoplasm map
    30. GTP:​RAF1|​S259_pho|​S621_pho|​S_pho|​open:​YWHAB@Cytoplasm map + ATP@Cytoplasm map map RAF1|​S259_pho|​S621_pho|​Y340_pho|​Y341_pho|​open@Cytoplasm map + ADP@Cytoplasm map
    31. MEK1*@Cytoplasm map + ATP@Cytoplasm map map MEK1*|​S218_pho|​S222_pho|​active@Cytoplasm map + ADP@Cytoplasm map
    32. MEK2*@Cytoplasm map + ATP@Cytoplasm map map MEK2*|​S_pho|​active@Cytoplasm map + ADP@Cytoplasm map
    33. MKNK1@Cytoplasm map + ATP@Cytoplasm map map MKNK1|​pho@Cytoplasm map + ADP@Cytoplasm map
    34. MKNK2@Cytoplasm map + ATP@Cytoplasm map map MKNK2|​pho@Cytoplasm map + ADP@Cytoplasm map
    35. Occludin*@Cytoplasm map + ATP@Cytoplasm map map Occludin*|​pho@Cytoplasm map + ADP@Cytoplasm map
    36. GJB1@Cytoplasm map + ATP@Cytoplasm map map GJB1|​pho@Cytoplasm map + ADP@Cytoplasm map
    37. GJA3@Cytoplasm map + ATP@Cytoplasm map map GJA3|​pho@Cytoplasm map + ADP@Cytoplasm map
    38. GJA1@Cytoplasm map + ATP@Cytoplasm map map GJA1|​pho@Cytoplasm map + ADP@Cytoplasm map
    39. Claudin1_2_3_4*@Cytoplasm map + ATP@Cytoplasm map map Claudin1_2_3_4*|​pho@Cytoplasm map + ADP@Cytoplasm map
    40. RAF1|​S_pho|​closed@Cytoplasm map + ATP@Cytoplasm map map RAF1|​S259_pho|​S621_pho|​S_pho|​closed@Cytoplasm map + ADP@Cytoplasm map

    As Catalyser:

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