a_re69

Reaction state_transition a_re69 map

degraded + NDUFS8@Mitochondrial inner membrane map + MT-ND5@Mitochondrial inner membrane map + MT-ND4@Mitochondrial inner membrane map + MT-ND4L@Mitochondrial inner membrane map + MT-ND3@Mitochondrial inner membrane map + MT-ND2@Mitochondrial inner membrane map + MT-ND1@Mitochondrial inner membrane map + MT-ND6@Mitochondrial inner membrane map FMN:​MT-ND1:​MT-ND2:​MT-ND3:​MT-ND4:​MT-ND4L:​MT-ND5:​MT-ND6:​NDUFA1:​NDUFA10:​NDUFA11:​NDUFA12:​NDUFA13:​NDUFA2:​NDUFA3:​NDUFA4:​NDUFA5:​NDUFA6:​NDUFA7:​NDUFA8:​NDUFA9:​NDUFAB1:​NDUFB1:​NDUFB10:​NDUFB11:​NDUFB2:​NDUFB3:​NDUFB4:​NDUFB5:​NDUFB6:​NDUFB7:​NDUFB8:​NDUFB9:​NDUFC1:​NDUFC2:​NDUFS1|​[2Fe-2S],[4Fe-4S],[4Fe-4S]:​NDUFS2:​NDUFS3:​NDUFS4:​NDUFS5:​NDUFS6:​NDUFS7|​[4Fe-4S]:​NDUFS8|​[4Fe-4S],[4Fe-4S]:​NDUFV1|​[4Fe-4S]:​NDUFV2|​[2Fe-2S]:​NDUFV3@Mitochondrial inner membrane map

Reaction regulators:

Catalysis
  1. AIFM1:​FAD@Mitochondrial inner membrane map
  2. NDUFAF2@Mitochondrial inner membrane map
  3. ACAD9:​ECSIT:​NDUFAF1@Mitochondrial inner membrane map



References
PMID:16200211
NDUFAF2
PMID:17344420
ECSIT:NDUFAF1
PMID:20816094
involvement of ACAD9 in the ECSIT:NDUFAF1 complex
PMID:16218961
NDUFAF1
PMID:15526035
AIF deficient cells exhibit a decrease content of complex I. It was proposed that AIF has a role in the biogenesis or maintenance of complex I
PMID:20025615
comprehensive review about complex I

Confidence
REF=5 FUNC=2


Leave a Reply