a_re486

Reaction heterodimer_association a_re486 map

APAF1@Cytoplasm map + HSP70*@Cytoplasm map APAF1:​HSP70*@Cytoplasm map

No reaction regulators

References
PMID:10934467
in 293, HeLa and Jurkat cells, interaction HSP70 – APAF1
in vitro, the interaction is ATP dependent
HSP70 interactions competes for oligomerization and formation of the apoptosome
PMID:10934466
in vitro, HSP70 blocks the recruitment of CASP9 into the apoptosome by binding to APAF1

Confidence
REF=2 FUNC=4


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