a_re484

Reaction state_transition a_re484 map

Caspase9*@Cytoplasm map cleaved~Caspase9*@Cytoplasm map

Reaction regulators:

Catalysis
  1. (d)ATP:​APAF1:​Cytochrome_C*|​ferroheme@Cytoplasm map
  2. NOD1@Cytoplasm map
Unknown_inhibition
  1. BIRC5|​T34_pho:​HBXIP@Cytoplasm map



References
PMID:15210107
reviews the differerent hypothesis concerning the biochemical events leading to activation of CASP9
PMID:12773388
in vitro, survivin and HBXIP together inhibits CASP9 processing and activation
in HT1080 cells, coexpression of BIRC5 and HBXIP suppresses staurosporin-induced apoptosis
in cell extracts from Hela transfected with siRNA against HBXIP, CYCS induced caspase activation is suppressed
PMID:10329646
by NOD1

Confidence
REF=2 FUNC=4


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