a_re448

Reaction state_transition a_re448 map

BCL2L11|​ubi@Cytoplasm map BimEL*|​ubi@Cytoplasm map

Reaction regulators:

Boolean_logic_gate_and
  1. CISH:​CUL2:​RBX1:​TCEB1:​TCEB2:​TCEB3@Cytoplasm map and NDRG1@Cytoplasm map
Catalysis
  1. CISH:​CUL2:​RBX1:​TCEB1:​TCEB2:​TCEB3@Cytoplasm map
  2. NDRG1@Cytoplasm map



References
PMID:19622774
BIM interacts with NDRG1 and with CISH and CUL2 in a NDRG1 dependent manner
NDRG1 expression destabilizes BIM

Confidence
REF=1 FUNC=3


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