a_re443

Reaction heterodimer_association a_re443 map

14-3-3*|​unk@Cytoplasm map + BimEL*|​S87_pho@Cytoplasm map 14-3-3*|​unk:​BimEL*|​S87_pho@Cytoplasm map

No reaction regulators

References
PMID:16282323
in HepG3 cells, insulin activates Akt but not ERK, and induces interaction between 14-3-3 and Bim (IP). In the same cell line, BimEL S87 phosphorylation was not assessed. The authors propose that the 14-3-3 bind to Akt-phosphorylated BimEL

Confidence
REF=1 FUNC=4


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