in CCL39 chinese hamster lung fibroblast cell line
in IL-3 dependent mouse pro-B cell line FL5.12, upon IL-3, ERK dependent phosphorylation of BimEL on S55, S65, S100 (mouse Bim)
in vitro, ERK2 phosphorylates mouse BimEL
in mouse BAF3 cells, in TF-1 human granulocyte macrophage- colony stimulating factor-dependent er ythroleukemia cell line, and in mouse embr yonic fibroblasts when IGF-1 was used as a survival factor, an upshift in BimEL (not BimL) electrophoretic mobility upon IL3. This upshift is lost in FL5.12 if phosphosites are mutated.