a_re392

Reaction state_transition a_re392 map

Fe2+:​PHD*@Cytoplasm map + ROS@Cytoplasm map Fe3+:​PHD*@Cytoplasm map

No reaction regulators

References
PMID:15369676
inhibition of PHD by ROS
PMID:20675386
questions the hypothesis of mitochondrial derived ROS inhibiting directly PHD upon hypoxia
proposes HIF1A stabilization upon respiratory chain inhibition would rather result from enhanced oxygen availability

Confidence
REF=2 FUNC=4


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