a_re248

Reaction state_transition a_re248 map

GPI|​hm2@Cytoplasm map GPI|​S185_pho|​hm4@Cytoplasm map

Reaction regulators:

Catalysis
  1. CK2_alpha_’*:​CK2_alpha_*:​CK_beta_*@Cytoplasm map



References
PMID:15637053
in human fibrosarcoma HT1080 cells, phosphorylation of GPI by CK2 decreases its enzymatic activity and (non-phosphorylatable or phospho-mimetic mutants)
in HT1080, knock-down of CK2 promotes GPI activity
in vitro, in HT1080 cells, phosphomimetic GPI mutant forms tetramers
in vitro, CK2 triggers GPI tetramerisation
PMID:11004567
in vitro CK2 mediated phosphorylation of GPI on S185
in HT1080 cells, Ser phosphorylation of GPI

Confidence
REF=2 FUNC=4


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