a_re245

Reaction state_transition a_re245 map

glucose@Cytoplasm map + ATP@Cytoplasm map glucose-6P@Cytoplasm map + ADP@Cytoplasm map

Reaction regulators:

Boolean_logic_gate_or
  1. HK1@Cytoplasm map and HK2@Cytoplasm map and HK3@Cytoplasm map and GCK@Cytoplasm map
Catalysis
  1. HK1@Cytoplasm map
  2. HK2@Cytoplasm map
  3. HK3@Cytoplasm map
  4. GCK@Cytoplasm map
  5. BAD|​S91_unk|​pho:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial outer membrane map
Inhibition
  1. glucose-6P@Cytoplasm map
  2. long-chain acyl-CoAs@Cytoplasm map



References
PMID:10531306
allosterinc inhibition of HK1 by glucose 6P
PMID:11078441
HK inhibition by long-chain acyl-CoAs
PMID:10760476
PMID:7130182
GCK inhibition by long-chain acyl-CoAs
PMID:12931191
in mouse liver mitochondria GCK activation by phosphorylated BAD within a mitochondrial protein complex

Confidence
REF=5 FUNC=3


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