a_re134

Reaction transcription a_re134 map

gBAX@Nucleus map rBAX@Nucleus map

Reaction regulators:

Catalysis
  1. p53*|​S15_pho|​active@Nucleus map
Inhibition
  1. NFKB1@Nucleus map
Unknown_inhibition
  1. CTBP*@Nucleus map



References
PMID:7834749
by p53
PMID:15613549
in HEK 293, by NFkB, upon expression of LMP1 protein (from EBV). More precisely, p65/p50 dimer inhibits BAX promoter activity whereas p50/p50 dimer is actually an transcriptional activator or BAX. However p65 has to be inhibited to see p50/p50 mediated activation of BAX
PMID:12676992
in MEF double knocked out by CTBP1 and CTBP2 (RT-PCR)

Confidence
REF=3 FUNC=4


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