a_re126

Reaction transcription a_re126 map

gPMAIP1@Nucleus map rPMAIP1@Nucleus map

Reaction regulators:

Catalysis
  1. HIF1A@Nucleus map
  2. p53*|​S15_pho|​active@Nucleus map
  3. E2F1@Nucleus map
Unknown_catalysis
  1. FOXO*@Nucleus map
Unknown_inhibition
  1. CTBP*@Nucleus map



References
PMID:14699081
in Saos-2, direct transactivation of NOXA by HIF1A during hypoxia, role of NOXA in hypoxia-induced cell death
PMID:16888645
in SH-EP, in NB15 neuroblastoma cell lines expressing a FOXO3-ER fusion, upon 4OHT. PMAIP knock down protects from apoptosis
PMID:12676992
in MEF by CTBP1 and CTBP2 (RT-PCR, double knocked out)
PMID:14684737
in NIH3T3, by E2F1

Confidence
REF=4 FUNC=4


Leave a Reply