a_re1111

Reaction state_transition a_re1111 map

MT-CO2@Mitochondrial inner membrane map + Cu2+@Mitochondrial inner membrane map Cu2+:​MT-CO2@Mitochondrial inner membrane map

Reaction regulators:

Boolean_logic_gate_and
  1. COX17@Mitochondrial inner membrane map and SCO2@Mitochondrial inner membrane map and SCO1@Mitochondrial inner membrane map
Catalysis
  1. SCO2@Mitochondrial inner membrane map
  2. SCO1@Mitochondrial inner membrane map
  3. COX17@Mitochondrial inner membrane map



References
PMID:15229189
SCO1, SCO2, and COX17 act cooperatively to load MT-CO2 with copper (copper chaperones)
PMID:19393246
in Hela, COX17 siRNA interferes with copper loading into MT-CO2
PMID:18458339
detailed description of COX17 mediated copper loading of SCO proteins, and interactions with the disulfide based modifications of these proteins

Confidence
REF=3 FUNC=3


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