a_re1000

Reaction state_transition a_re1000 map

BCL2|​unk@Mitochondrial outer membrane map cleaved~BCL2*@Mitochondrial outer membrane map

Reaction regulators:

Catalysis
  1. cleaved~Caspase3*@Cytoplasm map
Inhibition
  1. FKBP8@Mitochondrial outer membrane map



References
influenceDelete: reactants to re
hierarchical:post-MOMP
reactionType:casp.cleavage
PMID:10409669
CASP3 mediated cleavage of BCL2 in vitro and in HL60 cells or MCF7 with reconstituted CASP3 expression after exposure to staurosporine
no cleavage by CASP7
PMID:20139069
FKBP8 protects BCL2 from CASP3-mediated degradation

Confidence
REF=2 FUNC=5


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