CYCLINB na CDK1 MDM2 CYCLINA na CDKN1B CDK2 CYCLINE na CDKN1B CDK2 CCNE1 CCNE2 CYCLIND na AKT1 CCND1 CCND2 CCND3 GSK3B HSP90AA1 HSP90AA2 HSPC2 HSP90AB1 HSP90B1 HR na CSNK2A1 CSNK2A2 CSNK2B HSP90AA1 HSP90AA2 HSPC2 HSP90AB1 HSP90B1 CELL_CELL_ADHESIONS na PRKCA PRKCB PRKCE PRKCG PRKCZ PRKCD PRKCH PRKCQ PRKCI PRKCA CYTOSKELETON_POLARITY na CASP3 BER na NEDD4 PCNA AKT_MTOR na YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ SFN EIF4EBP1 AKT1 BCL2L1 EIF4B GSK3B IKBKB MAPKAP1 MLST8 MTOR PDCD4 PDPK1 AKT1S1 RBX1 RHEB RICTOR RPTOR RPS6KA1 RPS6KA3 RPS6KA2 RPS6KA6 RPS6KA4 PIM1 RPS6KA5 TSC1 TSC2 BTRC FBXW11 AKT1 AKT2 AKT3 CDH2 FOXO1 BCL2 PI3K_AKT_MTOR na YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ SFN EIF4EBP1 AKT1 APAF1 ATG13 BAD BAX BCL2L1 CBL CBLB CBLC CDK1 CDK4 CDK6 CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CSNK2A1 CSNK2A2 CSNK2B CUL1 CUL4A CUL4B CYCS CASP3 CASP8 CASP9 CASP9 CCND1 CCND2 CCND3 DCAF4 DCAF5 DCAF6 DCAF7 DCAF8 DCAF10 DCAF11 DCAF12 DCAF13 DCAF15 DCAF16 DCAF17 DEK DEPTOR UBA1 UBA2 UBA5 UBA6 UBA7 UBA3 UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H UBE2I UBE2J1 UBE2J2 UBE2K UBE2L3 UBE2L4 UBE2L6 UBE2M UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2Z UBE3A UBE3B UBE3C UBE3D EIF3A EIF3B EIF3C EIF3D EIF3E EIF3F EIF3G EIF3H EIF3I EIF3J EIF3K EIF3L EIF3M EIF4A1 EIF4A2 EIF4A3 EIF4B EIF4E EIF4E1B EIF4E2 EIF4E3 EIF4G1 EIF4G2 EIF4G3 NOS1 NOS2 NOS3 FBXW5 FBXW7 RB1CC1 FOXO3 FRK GAB1 GRB2 GSK3B HERC1 HSP90AA1 HSP90AA2 HSPC2 HSP90AB1 HSP90B1 IKBKB EIF4E2 MAPKAP1 MDM2 MLST8 MTOR NEDD4 PABPC1 PABPC3 PABP5 MYCBP2 PDCD4 PDPK1 PHLPP1 PHLPP2 PRKCA PRKCB PRKCE PRKCG PRKCZ PRKCD PRKCH PRKCQ PRKCI PPP2R1A PPP2R1B PPP2R2A PPP2CA PPP2CB PPP3R1 PPP3R2 PPP3CA PPP3CB PPP3CC AKT1S1 PRKCA PRR5 PTEN RAC1 RASA1 RASA2 RASA3 RASA4 HRAS KRAS NRAS RBX1 ALYREF RHEB RICTOR RNPS1 RPS6 RPTOR RPS6KA1 RPS6KA3 RPS6KA2 RPS6KA6 RPS6KA4 PIM1 RPS6KA5 RPS6KA1 RPS6KA2 EGFR ERBB2 ERBB3 ERBB4 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 PDGFRA PDGFRB RTKN SGK1 INPP5D POLDIP3 SKP1 SOS1 SOS2 SRRM1 SDC4 TSC1 TSC2 UBE2D1 UBE2D2 UBE2D3 ULK1 ULK2 RBM8A BTRC FBXW11 PIK3CA PIK3CB PIK3CD PIK3CG CDKN1A CDKN1B RPS6KB1 RPS6KB2 PIK3R1 PIK3R2 PIK3R3 AKT1 AKT2 AKT3 CDH2 BCOR CREBBP CREB3 CREB5 CDC34 RNF7 CDK2 DTL CKS1B CREB1 CREB3 CREB5 XPO1 CCNE1 CCNE2 DAXX DCAF4 DCAF5 DCAF6 DCAF7 DCAF8 DCAF10 DCAF11 DCAF12 DCAF13 DCAF15 DCAF16 DCAF17 DYRK1A DYRK1B E2F1 FOXO1 FOXO4 USP7 CHUK IKBKB IKBKE IKBKG IPO4 IPO5 IPO7 IPO8 IPO9 IPO11 IPO13 UHMK1 RNF123 UBAC1 PCNA RCHY1 PML PPP2R2A PPP2R2B PPP2R2C PPP2R2D PPP2R3A PPP2R3B PPP2R3C PPP2R4 PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E RUNX2 SKP2 TP53 BCL2 BCL6 BCL2L11 FASLG GADD45A GADD45B GADD45G MCL1 PINK1 PLK1 PLK2 PLK3 PLK4 BBC3 RAD51 RAD51L1 RAD51C RAD51L3 TRADD TNFSF10 CDKN2B CDKN2D S_CC_PHASE na CDK1 CDK2 E2F1 NER na CSNK2A1 CSNK2A2 CSNK2B CUL4A CUL4B RBX1 PCNA GADD45A GADD45B GADD45G G1_CC_PHASE na CDK4 CDK6 CCND1 CCND2 CCND3 CDK2 CCNE1 CCNE2 E2F1 APOPTOSIS_GENES na APAF1 BAD BAX FOXO3 HSP90AA1 HSP90AA2 HSPC2 HSP90AB1 HSP90B1 IKBKB MDM2 MLST8 MTOR PDCD4 PTEN RPTOR TSC2 CDKN1A CDKN1B E2F1 FOXO1 TP53 BCL2 BCL2L11 FASLG MCL1 BBC3 MIR214 MIR182 CASPASES na YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ SFN APAF1 BAX CDK1 CYCS CASP3 CASP9 IKBKB AKT1 AKT2 AKT3 CDH2 DYRK1A BCL2 BCL2L11 G2_CC_PHASE na CDK1 S_PHASE_CHECKPOINT na CUL1 RBX1 SKP1 BTRC FBXW11 SKP2 APOPTOSIS_ENTRY na AKT1 MDM2 E2F1 TP53 TLS na PCNA TNF_RESPONSE na YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ SFN CUL1 CASP8 IKBKB RAC1 RBX1 SKP1 BTRC FBXW11 P27KIP na AKT1 CDKN1B WNT_NON_CANONICAL na YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ SFN AKT1 BAD BAX BCL2L1 CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CUL1 CASP8 UBA1 UBA2 UBA5 UBA6 UBA7 UBA3 UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H UBE2I UBE2J1 UBE2J2 UBE2K UBE2L3 UBE2L4 UBE2L6 UBE2M UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2Z MDM2 PRKCA PRKCB PRKCE PRKCG PRKCZ PRKCD PRKCH PRKCQ PRKCI PPP2R1A PPP2R1B PTEN RAC1 RBX1 RPS6KA1 RPS6KA3 RPS6KA2 RPS6KA6 RPS6KA4 PIM1 RPS6KA5 EGFR ERBB2 ERBB3 ERBB4 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 PDGFRA PDGFRB RTKN SKP1 SDC4 AKT1 AKT2 AKT3 CDH2 XPO1 DAXX DYRK1A FOXO1 PML PPP2R2A PPP2R2B PPP2R2C PPP2R2D PPP2R3A PPP2R3B PPP2R3C PPP2R4 PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E TP53 FANCONI na HSP90AA1 HSP90AA2 HSPC2 HSP90AB1 HSP90B1 RBX1 MITOCH_METABOLISM na BAD BAX BCL2L1 CYCS NOS1 NOS2 NOS3 AKT1 AKT2 AKT3 CDH2 PML BCL2 BCL2L11 MCL1 G2_M_CHECKPOINT na YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ SFN CUL1 HSP90AA1 HSP90AA2 HSPC2 HSP90AB1 HSP90B1 MDM2 RBX1 SKP1 BTRC FBXW11 CREBBP CREB3 CREB5 SKP2 TP53 GADD45A GADD45B GADD45G E2F1 na CREBBP CREB3 CREB5 E2F1 P21CIP na AKT1 CDKN1A PCNA M_CC_PHASE na CDK1 MAPK na BAD CASP3 CASP9 FOXO3 GAB1 GRB2 GSK3B MDM2 PRKCA PRKCB PRKCE PRKCG PRKCZ PRKCD PRKCH PRKCQ PRKCI PPP2CA PPP2CB RAC1 RASA1 RASA2 RASA3 RASA4 HRAS KRAS NRAS RPS6KA1 RPS6KA3 RPS6KA2 RPS6KA6 RPS6KA4 PIM1 RPS6KA5 EGFR ERBB2 ERBB3 ERBB4 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 PDGFRA PDGFRB RTKN SOS1 SOS2 PIK3CA PIK3CB PIK3CD PIK3CG CDKN1A RPS6KB1 AKT1 AKT2 AKT3 CDH2 TP53 BCL2 GADD45A GADD45B GADD45G HIF1 na RBX1 MOMP_REGULATION na YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ SFN BAD BAX BCL2L1 CDK1 CUL1 GSK3B PRKCA RBX1 RPS6KA1 RPS6KA3 RPS6KA2 RPS6KA6 RPS6KA4 PIM1 RPS6KA5 SKP1 BTRC FBXW11 AKT1 AKT2 AKT3 CDH2 TP53 BCL2 BCL2L11 MCL1 BBC3 MMR na PCNA G1_S_CHECKPOINT na CUL1 SKP1 BTRC FBXW11 AKT1 AKT2 AKT3 CDH2 SKP2 TP53 EMT_REGULATORS na MDM2 E2F1 TP53 WNT_CANONICAL na CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CUL1 UBA1 UBA2 UBA5 UBA6 UBA7 UBA3 GSK3B PPP2CA PPP2CB RBX1 BTRC FBXW11 CREBBP CREB3 CREB5 XPO1 E2F1 TP53 CCND1 CCND2 CCND3 HEDGEHOG na YWHAB YWHAG YWHAH YWHAE YWHAQ YWHAZ SFN CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CUL1 CASP9 UBA1 UBA2 UBA5 UBA6 UBA7 UBA3 UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H UBE2I UBE2J1 UBE2J2 UBE2K UBE2L3 UBE2L4 UBE2L6 UBE2M UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2Z UBE3A UBE3B UBE3C UBE3D GSK3B PPP2R1A PPP2R1B PPP2R2A PPP2CA PPP2CB RAC1 RASA1 RASA2 RASA3 RASA4 HRAS KRAS NRAS RBX1 SKP1 TSC1 TSC2 BTRC FBXW11 PIK3CA PIK3CB PIK3CD PIK3CG RPS6KB2 PIK3R1 PIK3R2 PIK3R3 AKT1 AKT2 AKT3 CDH2 CREBBP CREB3 CREB5 CDC34 XPO1 DYRK1A BCL2 CCND1 CCND2 CCND3 BCL2L11 PTEN BBC3